As Summer Heats Up, CHOP Researchers Study Caregiver Attitudes Toward Pediatric Vehicular Heatstroke

–While those who were thought to put children at risk were viewed negatively, a large number of caregivers supported education efforts and technology use to reduce heatstroke risk– PHILADELPHIA, June 21, 2023 /PRNewswire/ — Despite prevention efforts, a child dies of heatstroke in a vehicle approximately once every 10 days. According to a new survey … Read more

CHOP Researchers Develop Universal MHC Molecules that Can be Produced Rapidly at Scale

–The molecules open the door for development of immunotherapies that are truly universal and work across HLA types, regardless of patient ancestry— PHILADELPHIA, June 13, 2023 /PRNewswire/ — Class I major histocompatibility complex (MHC-I) proteins play an essential role in the immune system of all jawed vertebrates. The MHC-I displays peptide fragments of proteins from … Read more

Self-Esteem of Kids with Short Stature Tied to Social Supports, Not Height

–New study by Children’s Hospital of Philadelphia shows that in otherwise healthy short youth, quality of life is associated with how well-supported they feel, rather than with their height— PHILADELPHIA, June 12, 2023 /PRNewswire/ — Challenging the assumption that short stature negatively impacts children and adolescents’ self-esteem, a new study by researchers at Children’s Hospital of … Read more

Children’s Hospital of Philadelphia Celebrates 27th Annual Fetal Surgery Family Reunion at the Philadelphia Zoo

PHILADELPHIA, June 5, 2023 /PRNewswire/ — Yesterday, more than 3,000 people gathered at the Philadelphia Zoo to celebrate the 27th Children’s Hospital of Philadelphia (CHOP) Fetal Family Reunion, representing patients and families from across the country. The event, hosted by CHOP’s Richard D. Wood Jr. Center for Fetal Diagnosis and Treatment (CFDT), provides an opportunity for those treated … Read more

CHOP Researchers Show that IgA Fine Tunes the Body’s Interactions with Microbes

–Study found variability in IgA levels in the bloodstream versus the gut, which may help explain why some with IgA deficiency have symptoms, while others do not– PHILADELPHIA, May 26, 2023 /PRNewswire/ — IgA deficiency is the most common primary immune deficiency worldwide, but its presentation has puzzled physcians and researchers. Some with the disorder … Read more

CHOP Researchers Comprehensively Assess the Safety of Using Your Head in Youth Soccer

–While a small number of relatively low impact soccer headers did not have detrimental effects, teen soccer players should still be trained to head the ball safely — PHILADELPHIA, May 24, 2023 /PRNewswire/ — Repeatedly heading a soccer ball has been previously associated with negative long-term brain health for professional players. However, in a new … Read more

New Computational Tool Identifies Novel Targets for Cancer Immunotherapy

–Study led by CHOP and UCLA demonstrates the power of using big data and multi-omics to discover novel tumor antigens derived from alternative RNA splicing– PHILADELPHIA, May 17, 2023 /PRNewswire/ — Researchers at Children’s Hospital of Philadelphia (CHOP) and the University of California, Los Angeles (UCLA) have developed a computational platform capable of discovering tumor … Read more